Warfarin is a medication that, with few exceptions, is dosed to effect. When the INR does not respond as predicted, it is important to consider possible causes before the warfarin dose is adjusted. Because Coumadin (warfarin) is so closely monitored with blood tests the right answer is the limit is the dose that gets you to your goal inr. 362 CLEVELAND CLINIC JOURNAL OF MEDICINE VOLUME 70 • NUMBER 4 APRIL 2003 verted to their activated forms. Warfarin, as a vitamin K antagonist, interferes with this Weight-based dosage requirements for warfarin have been determined to be age-dependent. In a large cohort of pediatric patients (n = 262), infants required an average daily dose of 0.33 mg/kg while adolescents required an average daily dose of 0.09 mg/kg to maintain the INR between 2 and 3. Specific dosing recommendations for use in pediatric patients are not available in the FDA-approved. Medscape - Deep vein thrombosis, pulmonary embolism, recurrent myocardial infarction-specific dosing for Coumadin, Jantoven (warfarin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Learn about Coumadin (Warfarin Sodium) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Detailed Warfarin dosage information for adults and children. Includes dosages for Myocardial Infarction, Prevention of Thromboembolism in Atrial Fibrillation, Myocardial Infarction - Prophylaxis and more; plus renal, liver and dialysis adjustments. This dosage information is for warfarin oral tablet. All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on: All possible dosages and. WARFARIN DRUG UTILIZATION EVALUATION. Criteria for warfarin administration were developed that were supported by the medical literature and approved by the Drug Utilization Evaluation Subcommittee of the Pharmacy and Therapeutics Committee. Warfarin is an anticoagulant (blood thinner). Warfarin reduces the formation of blood clots. Warfarin is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions.